Published in
Royal Society of Chemistry, Chemical Science, 21(10), p. 5603-5615, 2019
DOI: 10.1039/c9sc00684b
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Development of<sup>68</sup>Ga-labelled ultrasound microbubbles for whole-body PET imaging
Journal article published in 2019 by
Javier Hernández-Gil 
,
Marta Braga ,
Bethany I. Harriss,
Laurence S. Carroll ,
Chee Hau Leow,
Meng-Xing Tang,
Eric O. Aboagye ,
Nicholas J. Long
,
Marta Braga ,
Bethany I. Harriss,
Laurence S. Carroll ,
Chee Hau Leow,
Meng-Xing Tang,
Eric O. Aboagye ,
Nicholas J. Long
This paper is made freely available by the publisher.
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Abstract
We report a rapid and efficient method for labelling ultrasound microbubble (MB) agents with a generator-produced PET isotope using a facile ligation between atrans-cyclooctene-modified phospholipid and a new68Ga-HBED-CC-tetrazine tracer. This method provides accessible solutions forin vivotracking of MBs.