Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 6(63), 2019
DOI: 10.1128/aac.00163-19
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Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects
Journal article published in 2019 by
Laura L. Kovanda 
,
Sean M. Sullivan,
Larry R. Smith,
Amit V. Desai,
Pete L. Bonate,
William W. Hope
,
Sean M. Sullivan,
Larry R. Smith,
Amit V. Desai,
Pete L. Bonate,
William W. Hope
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
VL-2397, a novel, systemic antifungal agent, has potent in vitro and in vivo fungicidal activity against Aspergillus species. Plasma concentrations from a phase 1 study were used to construct a population pharmacokinetic (PPK) model for VL-2397.