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Oxford University Press, Nucleic Acids Research, Web Server(34), p. W147-W151, 2006

DOI: 10.1093/nar/gkl289

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SABBAC: online Structural Alphabet-based protein BackBone reconstruction from Alpha-Carbon trace

Journal article published in 2006 by Julien Maupetit, R. Gautier, Pierre Tufféry ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

SABBAC is an on-line service devoted to protein backbone reconstruction from alpha-carbon trace. It is based on the assembly of fragments taken from a library of reduced size, selected from the encoding of the protein trace in a hidden Markov model-derived structural alphabet. The assembly of the fragments is achieved by a greedy algorithm, using an energy-based scoring. Alpha-carbon coordinates remain unaffected. SABBAC simply positions the missing backbone atoms, no further refinement is performed. From our tests, SABBAC performs equal or better than other similar on-line approach and is robust to deviations on the alpha-carbon coordinates. It can be accessed at http://bioserv.rpbs.jussieu.fr/SABBAC.html.