Published in
Elsevier, Annals of Oncology, 11(19), p. 1870-1874, 2008
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- [www.ncbi.nlm.nih.gov] | PDF
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Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer
Journal article published in 2008 by
K. P. M. Suijkerbuijk 
,
M. J. Fackler,
S. Sukumar,
C. H. van Gils,
T. van Laar,
E. van der Wall,
M. Vooijs,
P. J. van Diest
,
M. J. Fackler,
S. Sukumar,
C. H. van Gils,
T. van Laar,
E. van der Wall,
M. Vooijs,
P. J. van Diest
This paper is made freely available by the publisher.
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Abstract
Background: Promoter methylation is a common epigenetic mechanism to silence tumor suppressor genes during breast cancer development. We investigated whether BRCA1-associated breast tumors show cancer-predictive methylation patterns similar to those found in sporadic tumors.