Published in
American Society for Microbiology, Applied and Environmental Microbiology, 2(78), p. 599-603, 2012
DOI: 10.1128/aem.06992-11
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Streptomycin-Induced Expression in Bacillus subtilis of YtnP, a Lactonase-Homologous Protein That Inhibits Development and Streptomycin Production in Streptomyces griseus
Journal article published in 2011 by
Johannes Schneider,
Ana Yepes,
Juan C. Garcia-Betancur,
Isa Westedt,
Benjamin Mielich,
Daniel López 
This paper is made freely available by the publisher.
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Abstract
ABSTRACT Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus . ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus .