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Nature Research, Nature Immunology, 10(13), p. 942-943, 2012

DOI: 10.1038/ni.2421

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Yoking OX40 to regulation of IL-9

Journal article published in 2012 by Ritobrata Goswami, Mark H. Kaplan ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The secretion of cytokines by helper T cells is affected by the cytokine environment and by costimulatory signals. Engagement of the receptor OX40 on T cells increases expression of the transcription factor TRAF6, activates the alternative transcription factor NF-κB pathway and induces the production of interleukin 9.