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American Society for Microbiology, Infection and Immunity, 5(87), 2019

DOI: 10.1128/iai.00064-19

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Leishmania donovani Lipophosphoglycan Increases Macrophage-Dependent Chemotaxis of CXCR6-Expressing Cells via CXCL16 Induction

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

CXCL16 is a multifunctional chemokine that is highly expressed by macrophages and other immune cells in response to bacterial and viral pathogens; however, little is known regarding the role of CXCL16 during parasitic infections. The protozoan parasite Leishmania donovani is the causative agent of visceral leishmaniasis.