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American Association for the Advancement of Science, Science Signaling, 617(13), 2020

DOI: 10.1126/scisignal.aaw5885

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A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Data provided by SHERPA/RoMEO

Abstract

A conserved amino acid residue in the ligand binding site of class A GPCRs regulates receptor interactions with β-arrestin.