Published in

American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 4(63), 2019

DOI: 10.1128/aac.02328-18

Links

Tools

Export citation

Search in Google Scholar

Population Pharmacokinetics with Monte Carlo Simulations of Gentamicin in a Population of Severely Ill Adult Patients from Sub-Saharan Africa

Journal article published in 2019 by Jeannet C. Bos, Jan M. Prins ORCID, Mabor C. Mistício, Ginto Nunguiane, Cláudia N. Lang, José C. Beirão, Ron A. A. Mathôt ORCID, Reinier M. van Hest
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

In sub-Saharan Africa (SSA), gentamicin is commonly used for severe infections in non-intensive-care-unit (ICU) settings, but pharmacokinetic and pharmacodynamic data for this specific population are lacking. We performed a population pharmacokinetic study in an adult Mozambican non-ICU hospital population treated with gentamicin ( n = 48) and developed a pharmacokinetic model using nonlinear mixed-effects modeling.