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Public Library of Science, PLoS ONE, 8(8), p. e69957, 2013

DOI: 10.1371/journal.pone.0069957

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Pathology Influences Blood Pressure Change following Vagal Stimulation in an Animal Intubation Model

Journal article published in 2013 by Peter Jones, Laurent Guillaud, Christophe Desbois, Jean-Francois Benoist, Helene Combrisson, Stephane Dauger, Mark J. Peters ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The haemodynamic response to critical care intubation is influenced by the use of sedation and relaxant drugs and the activation of the vagal reflex. It has been hypothesized that different disease states may have a contrasting effect on the cardiovascular response to vagal stimulation. Our objective was to determine whether the blood pressure response to vagal stimulation was modified by endotoxaemia or hypovolaemia.