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Elsevier, Cell Stem Cell, 6(13), p. 635-636, 2013

DOI: 10.1016/j.stem.2013.11.017

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Inducing Cellular Aging: Enabling Neurodegeneration-in-a-Dish

Journal article published in 2013 by Kristen J. Brennand ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The immaturity of neurons differentiated from human induced pluripotent stem cells (hiPSCs) presents difficulties for modeling late-onset neurodegenerative disorders such as Parkinson’s disease (PD). Now, Miller et al. (2013) provide a strategy for inducing aging-related phenotypes in hiPSC-derived neurons, enabling in vitro study of late-onset neurodegenerative diseases.