Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(63), 2019
DOI: 10.1128/aac.01931-18
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In Vivo Efficacy of Humanized WCK 5222 (Cefepime-Zidebactam) Exposures against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Thigh Model
Journal article published in 2018 by
Safa S. Almarzoky Abuhussain 
,
Lindsay M. Avery,
Kamilia Abdelraouf,
David P. Nicolau
,
Lindsay M. Avery,
Kamilia Abdelraouf,
David P. Nicolau
This paper is made freely available by the publisher.
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Abstract
Herein, we describe the in vivo efficacy of human-simulated WCK 5222 (cefepime-zidebactam) exposure against carbapenem-resistant Acinetobacter baumannii strains in a neutropenic murine thigh infection model. Five of the six isolates examined expressed OXA-23 or OXA-24.