Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(63), 2019
DOI: 10.1128/aac.01316-18
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Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus
Journal article published in 2018 by
Matthias Richard,
Ana Victoria Gutiérrez,
Albertus Viljoen,
Daniela Rodriguez-Rincon,
Françoise Roquet-Baneres,
Mickael Blaise,
Isobel Everall,
Julian Parkhill 
,
R. Andres Floto,
Laurent Kremer
,
R. Andres Floto,
Laurent Kremer
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
New therapeutic approaches are needed against Mycobacterium abscessus , a respiratory mycobacterial pathogen that evades efforts to successfully treat infected patients. Clofazimine and bedaquiline, two drugs used for the treatment of multidrug-resistant tuberculosis, are being considered as alternatives for the treatment of lung diseases caused by M. abscessus .