Dissemin is shutting down on January 1st, 2025

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Elsevier, Acta Tropica, 3(102), p. 206-211, 2007

DOI: 10.1016/j.actatropica.2007.05.002

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Evaluation of the EIE-IgM Leptospirose assay for the serodiagnosis of leptospirosis

Journal article published in 2007 by Alan J. A. McBride ORCID, Fernanda A. Pereira, Emilson D. da Silva, Rosan B. de Matos, Edimilison D. da Silva, Antônio G. P. Ferreira, Mitermayer G. Reis ORCID, Albert I. Ko
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Abstract

Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptospirosis, respectively, and a specificity of 93-100% (total healthy and patient control subjects evaluated, 486). These findings indicate that the assay will be useful for diagnosis of this emerging infectious disease in Brazil and other developing countries.