ABSTRACT Jaboticaba is a fruit with high nutritional potential with beneficial effects for health. The aims of this work were the optimization of the extraction of phenolic compounds (PhC) from freeze-dried jaboticaba peel (FJP) as a function of the stirring time (ST) and solvent volume (SV) and to study the edaphic effect on the physical-chemical composition of FJP from five orchards. In the first stage, a 2-factor, 2-level central composite designs combined with the Response Surface Methodology and desirability function was used. In the second stage, a one-way analysis of variance was used to investigate the edaphic effect on the responses. Total phenols (Tph), tannins (Ta), total monomeric anthocyanins (TMA), color index (CI) and tone responses (Ton) were analyzed. A second-order polynomial model was used for predicting of the first stage dates. The data from the second experiment were evaluated using analysis of variance, Tukey’s test, and t-test. The optimal conditions for the PhC were 64 mL and 75 min. Under the optimum conditions, the corresponding predicted response values for PhC were 33.5, 7.91, and 5.57 mg g-1 and 0.893 u.a. and 0.833 for Tph, Ta, TMA, CI, and Ton, respectively. According to the type of soil, different PhC values were found in FJP extracts. In nutrient-poor soils, highest levels of PhC, high CI and low tone were found.