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Royal Society of Chemistry, RSC Advances, 65(8), p. 37503-37507, 2018

DOI: 10.1039/c8ra07627h

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Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction

Journal article published in 2018 by Mzilikazi F. Khumalo, Ekemini D. Akpan ORCID, Praveen K. Chinthakindi ORCID, Edikarlos M. Brasil ORCID, Kamal K. Rajbongshi ORCID, Maya M. Makatini, Thavendran Govender ORCID, Hendrik G. Kruger ORCID, Tricia Naicker ORCID, Per I. Arvidsson ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Herein, we report the preparation of 1,2,4-thiadiazinane 1,1-dioxides from reaction of β-aminoethane sulfonamides with dichloromethane, dibromomethane and formaldehyde as methylene donors.