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Biology at the Single Molecule Level, p. 115-140

DOI: 10.1016/b978-008044031-6/50034-3

Elsevier, Progress in Biophysics and Molecular Biology, 1-2(74), p. 115-140, 2000

DOI: 10.1016/s0079-6107(00)00018-3

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Twisting and stretching single DNA molecules

Journal article published in 2000 by Jean-François Allemand ORCID, Terence R. Strick, Vincent Croquette, David Bensimon
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The elastic properties of DNA are essential for its biological function. They control its bending and twisting as well as the induction of structural modifications in the molecule. These can affect its interaction with the cell machinery. The response of a single DNA molecule to a mechanical stress can be precisely determined in single-molecule experiments which give access to an accurate measurement of the elastic parameters of DNA.