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Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 12(55), p. 8614-8625

DOI: 10.1167/iovs.14-15693

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The Role of the Hypoxia Response in Shaping Retinal Vascular Development in the Absence of Norrin/Frizzled4 Signaling

Journal article published in 2014 by Amir Rattner ORCID, Yanshu Wang, Yulian Zhou, John Williams, Jeremy Nathans
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The hypoxia response drives compensatory vascular hypertrophy and increases vascular permeability in the context of defective Norrin/Fz4 signaling.