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American Association for the Advancement of Science, Science Translational Medicine, 492(11), 2019

DOI: 10.1126/scitranslmed.aau8465

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Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition

Journal article published in 2019 by William P. Esler ORCID, Gregory J. Tesz ORCID, Marc K. Hellerstein, Carine Beysen, Raja Sivamani ORCID, Scott M. Turner, Steven M. Watkins, Paul A. Amor, Santos Carvajal-Gonzalez ORCID, Frank J. Geoly ORCID, Kathleen E. Biddle, Julie J. Purkal ORCID, Mark Fitch ORCID, Clare Buckeridge, Annette M. Silvia ORCID and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

De novo lipogenesis is essential for human sebum production, and increased lipogenic flux accounts for excessive sebum production in acne vulgaris.