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American Association for the Advancement of Science, Science Translational Medicine, 521(11), 2019

DOI: 10.1126/scitranslmed.aaw8283

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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction

Journal article published in 2019 by Vladimir V. Senatorov, Aaron R. Friedman ORCID, Dan Z. Milikovsky ORCID, Jonathan Ofer ORCID, Rotem Saar-Ashkenazy ORCID, Adiel Charbash, Naznin Jahan, Gregory Chin ORCID, Eszter Mihaly, Jessica M. Lin ORCID, Harrison J. Ramsay ORCID, Ariana Moghbel ORCID, Marcela K. Preininger, Chelsy R. Eddings ORCID, Helen V. Harrison and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Age-related breakdown of blood-brain barrier activates astrocytic TGFβ signaling to cause neural dysfunction and cognitive impairment.