Published in
American Association for the Advancement of Science, Science Advances, 5(5), 2019
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PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy
Journal article published in 2019 by
Hanming Zhang 
,
Bo Pan,
Penglong Wu,
Nirmal Parajuli,
Mark D. Rekhter,
Alfred L. Goldberg,
Xuejun Wang
,
Bo Pan,
Penglong Wu,
Nirmal Parajuli,
Mark D. Rekhter,
Alfred L. Goldberg,
Xuejun Wang
This paper is made freely available by the publisher.
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Abstract
PDE1 inhibition enhances the proteasome and protects against proteinopathy and heart failure with preserved ejection fraction.