Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD
Journal article published in 2019 by
Brent H. Koehn 
,
Asim Saha,
Cameron McDonald-Hyman,
Michael Loschi ,
Govindarajan Thangavelu,
Lie Ma,
Michael Zaiken ,
Josh Dysthe,
Walker Krepps,
Jamie Panthera,
Keli Hippen ,
Stephen C. Jameson,
Jeffrey S. Miller,
Matthew A. Cooper,
Christopher J. Farady
and other authors.
,
Asim Saha,
Cameron McDonald-Hyman,
Michael Loschi ,
Govindarajan Thangavelu,
Lie Ma,
Michael Zaiken ,
Josh Dysthe,
Walker Krepps,
Jamie Panthera,
Keli Hippen ,
Stephen C. Jameson,
Jeffrey S. Miller,
Matthew A. Cooper,
Christopher J. Farady
and other authors.
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Abstract
These studies demonstrate how activation of the NLRP3 inflammasome pathway influences the function of myeloid-derived suppressor cells (MDSCs) in the setting of acute graft-versus-host disease (aGVHD).