Published in
American Society of Hematology, Blood Advances, 21(3), p. 3337-3350, 2019
DOI: 10.1182/bloodadvances.2019000689
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Large-scale in-vitro production of red blood cells from human peripheral blood mononuclear cells
Journal article published in 2019 by
Steven Heshusius,
Esther Heideveld,
Patrick Burger,
Marijke Thiel-Valkhof,
Erica Sellink,
Eszter Varga,
Elina Ovchynnikova,
Anna Visser,
Joost H. A. Martens 
,
Marieke von Lindern ,
Emile van den Akker
,
Marieke von Lindern ,
Emile van den Akker
This paper is made freely available by the publisher.
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Abstract
Key Points This article provides a defined GMP-grade medium and erythroid culture protocol, resulting in >90% enucleated RBC. This article provides a high-resolution database of RNA expression dynamics at daily intervals during terminal erythroid differentiation.