Published in
American Association for the Advancement of Science, Science Translational Medicine, 464(10), 2018
DOI: 10.1126/scitranslmed.aat3487
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Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma
Journal article published in 2018 by
Liran Zhou 
,
Hongmei Husted ,
Todd Moore,
Mason Lu,
Defeng Deng,
Yan Liu ,
Vijaya Ramachandran,
Thiruvengadam Arumugam,
Christof Niehrs,
Huamin Wang,
Paul Chiao,
Jianhua Ling,
Michael A. Curran ,
Anirban Maitra ,
Mien-Chie Hung
and other authors.
,
Hongmei Husted ,
Todd Moore,
Mason Lu,
Defeng Deng,
Yan Liu ,
Vijaya Ramachandran,
Thiruvengadam Arumugam,
Christof Niehrs,
Huamin Wang,
Paul Chiao,
Jianhua Ling,
Michael A. Curran ,
Anirban Maitra ,
Mien-Chie Hung
and other authors.
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Abstract
DKK3 is produced by the stroma in pancreatic cancer, promotes tumor progression and resistance to therapy, and is a therapeutic target.