ObjectiveTo report the outcomes of cataract surgery performed by non-physician cataract surgeons due to lack of ophthalmologists in remote areas of North Cameroon.DesignProspective cohort study.SettingThe main centre of the non-governmental organisation Ophtalmo Sans Frontières in Lagdo.Participants and interventionsAge-related cataract surgery performed between 28 November 2016 and 17 May 2017.Main outcomes measuresThe main outcome measure was presenting visual acuity (PVA) 1–4 weeks after surgery, classified according to the WHO as good (PVA ≥6/18), borderline (PVA 6/60–6/18) and poor (PVA <6/60). The WHO definition of blindness (visual acuity <3/60) and severe visual acuity (visual acuity 3/60–6/60) was used to assess the proportion of patients with a change in WHO category.ResultsWe included 474 eyes of 474 patients; the mean (SD) age was 63.9 (15) years (42.2% female). At 1–4 weeks after surgery, the surgical outcome was good for 170 patients (41.1%), borderline for 213 (51.5%) and poor for 31 (7.5%). In all, 224 patients (47.2%) had blindness or severe visual impairment before cataract surgery and 22 (5.3%) at 1–4 weeks after surgery. Poor visual outcome was associated with older age (p=0.018), preoperative blindness or severe impairment (p=0.012) and surgical complications (p=0.019).ConclusionBlindness and severe visual impairment were significantly decreased in the early postoperative period. Poor outcomes were associated with older age, low preoperative binocular visual acuity and intraoperative complications. Non-physician cataract surgeons may compensate for the lack of ophthalmologists in remote areas of low-income and middle-income countries.