American Society of Hematology, Blood, 14(132), p. 1507-1518
DOI: 10.1182/blood-2018-01-824607
Full text: Unavailable
Key Points North American ATLL has a distinct genomic landscape with a high frequency of prognostic epigenetic mutations, including EP300 mutations. ATLL samples with mutated EP300 have compromised p53 function and are selectively sensitive to decitabine treatment.