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Elsevier, Experimental Cell Research, 9(319), p. 1324-1330

DOI: 10.1016/j.yexcr.2012.12.009

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miRNAs in endothelial cell signaling: the endomiRNAs

Journal article published in 2012 by Massimo Mm Santoro ORCID, S. Nicoli
This paper is available in a repository.
This paper is available in a repository.

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Abstract

microRNAs (miRNAs) have a pivotal role during the formation and function of the cardiovascular system. More than 300 miRNAs have been currently found within the mammalian genome, however only few specific miRNAs, named endomiRNAs, showed conseved endothelial cell expression and function. In this review we present an overview of the currently know endo miRNAs, focusing on their genome localization, processing and target gene repression during vasculogenesis and angiogenesis.