Dissemin is shutting down on January 1st, 2025

Published in

American Association for the Advancement of Science, Science Signaling, 549(11), 2018

DOI: 10.1126/scisignal.aau0597

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Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1

Journal article published in 2018 by Sam A. Jamieson ORCID, Zheng Ruan ORCID, Abigail E. Burgess ORCID, Jack R. Curry ORCID, Hamish D. McMillan ORCID, Jodi L. Brewster ORCID, Anita K. Dunbier ORCID, Alison D. Axtman ORCID, Natarajan Kannan, Peter D. Mace ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Allosteric regulation of the pseudokinase TRIB1 reveals the therapeutic potential of kinase inhibitors.