WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Chan, Edmond M.; Shibue, Tsukasa; McFarland, James M.; Gaeta, Benjamin; Ghandi, Mahmoud; Dumont, Nancy; Gonzalez, Alfredo; McPartlan, Justine S.; Li, Tianxia; Zhang, Yanxi; Bin Liu, Jie; Lazaro, Jean-Bernard; Gu, Peili; Piett, Cortt G.; Apffel, Annie; Ali, Syed O.; Deasy, Rebecca; Keskula, Paula; Ng, Raymond W. S.; Roberts, Emma A.; Reznichenko, Elizaveta; Leung, Lisa; Alimova, Maria; Schenone, Monica; Islam, Mirazul; Maruvka, Yosef E.; Liu, Yang; Roper, Jatin; Raghavan, Srivatsan; Giannakis, Marios; Tseng, Yuen-Yi; Nagel, Zachary D.; D’Andrea, Alan; Root, David E.; Boehm, Jesse S.; Getz, Gad; Chang, Sandy; Golub, Todd R.; Tsherniak, Aviad; Vazquez, Francisca; Bass, Adam J.

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Nature Research, Nature, 7753(568), p. 551-556, 2019

DOI: 10.1038/s41586-019-1102-x

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WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Journal article published in 2019 by Edmond M. Chan, Tsukasa Shibue, James M. McFarland, Benjamin Gaeta, Mahmoud Ghandi, Nancy Dumont, Alfredo Gonzalez

, Justine S. McPartlan, Tianxia Li, Yanxi Zhang, Jie Bin Liu, Jean-Bernard Lazaro, Peili Gu, Cortt G. Piett, Annie Apffel

and other authors.

This paper is made freely available by the publisher.

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WRN helicase is a synthetic lethal target in microsatellite unstable cancers