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Public Library of Science, PLoS ONE, 1(7), p. e29684, 2012

DOI: 10.1371/journal.pone.0029684

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Straightforward Inference of Ancestry and Admixture Proportions through Ancestry-Informative Insertion Deletion Multiplexing

Journal article published in 2012 by Rui Pereira, Sidney Emanuel Batista dos Santos, Christopher Phillips ORCID, Nádia Pinto, Carla Santos, Sidney Emanuel Batista dos Santos, António Amorim ORCID, Ángel Carracedo, Leonor Gusmão
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Ancestry-informative markers (AIMs) show high allele frequency divergence between different ancestral or geographically distant populations. These genetic markers are especially useful in inferring the likely ancestral origin of an individual or estimating the apportionment of ancestry components in admixed individuals or populations. The study of AIMs is of great interest in clinical genetics research, particularly to detect and correct for population substructure effects in case-control association studies, but also in population and forensic genetics studies.