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Wiley, Angewandte Chemie International Edition, 48(50), p. 11417-11420, 2011

DOI: 10.1002/anie.201104449

Wiley, Angewandte Chemie, 48(123), p. 11619-11622, 2011

DOI: 10.1002/ange.201104449

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Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration**

Journal article published in 2011 by Vikash P. Chauhan, Zoran Popović, Ou Chen, Jian Cui ORCID, Dai Fukumura, Moungi G. Bawendi, Rakesh K. Jain
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This paper is available in a repository.

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Abstract

Shape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half-life.