Inflammatory interference of memory formation
Journal article published in 2014 by
Akshay T. Krishnamurty 
,
Marion Pepper
,
Marion Pepper
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Abstract
CD8+ memory T cells are critical for immunity against intracellular pathogens. Epidemiological evidence demonstrates that bystander infection can impact immune responses to co-infection or vaccination. A recent paper in Immunity demonstrates that persistent bystander inflammation can negatively impact CD8+ T cell effector to memory transition and protection from subsequent infection.