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American Society of Hematology, Blood, 4(128), p. 519-528, 2016

DOI: 10.1182/blood-2015-11-683847

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Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points A platform for the generation of clinical-grade CD19-CAR–modified TSCM. CD19-CAR–modified TSCM mediate superior antitumor responses compared with CD19-CAR T cells currently used in clinical trials.