Published in
American Association for the Advancement of Science, Science Translational Medicine, 422(10), 2018
DOI: 10.1126/scitranslmed.aan3128
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Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis
Journal article published in 2018 by
Duncan B. Richards 
,
Louise M. Cookson,
Sharon V. Barton,
Lia Liefaard,
Thirusha Lane,
David F. Hutt,
James M. Ritter ,
Marianna Fontana,
James C. Moon ,
Julian D. Gillmore,
Ashutosh Wechalekar,
Philip N. Hawkins ,
Mark B. Pepys
,
Louise M. Cookson,
Sharon V. Barton,
Lia Liefaard,
Thirusha Lane,
David F. Hutt,
James M. Ritter ,
Marianna Fontana,
James C. Moon ,
Julian D. Gillmore,
Ashutosh Wechalekar,
Philip N. Hawkins ,
Mark B. Pepys
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Abstract
Repeat cycles of miridesap, to deplete circulating serum amyloid P component (SAP), followed by the anti-SAP antibody, dezamizumab, cleared visceral amyloid deposits in patients with systemic amyloidosis.