Dissemin is shutting down on January 1st, 2025

Published in

American Association for the Advancement of Science, Science, 6330(355), p. 1211-1215, 2017

DOI: 10.1126/science.aaf8451

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Inflammation boosts bacteriophage transfer between Salmonella spp.

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

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Preprint: archiving allowed
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Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

The parasite of my parasite is my friend? Virulence factors of pathogenic bacteria can be swapped by means of bacterial viruses called phages. In turn, the pathogenic bacteria are under attack by the hosts' immune responses. Diard et al. discovered that SopEϕ, a phage parasite of pathogenic Salmonella species, is encouraged to spread between bacteria by the mouse host's inflammatory responses. Conversely, mucosal vaccination against Salmonella reduced inflammatory responses and curbed the transfer of SopEϕ to naïve bacteria. Science , this issue p. 1211