Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, Ingrid E.; Lin, Honghuang; Ie, Christophersen; Rienstra, Michiel; Li, Molong; Roselli, Carolina; Arking, Dan E.; Müller-Nurasyid, Martina; Smith, J. Gustav; Smith, Albert V.; Yin, Xiaoyan; Albert, Christine M.; Dörr, Marcus; Geelhoed, Bastiaan; Tucker, Nathan R.; Barnard, John; Bihlmeyer, Nathan A.; Low, Siew-Kee; Weeke, Peter E.; Brody, Jennifer A.; Niemeijer, Maartje N.; Trompet, Stella; Hopewell, Jemma C.; Debette, Stephanie; Chauhan, Ganesh; Huffman, Jennifer; Chaffin, Mark; Yang, Qiong; Worrall, Bradford B.; Gustafsson, Stefan; Paré, Guillaume; Kamatani, Yoichiro; Schurmann, Claudia; Kleber, Marcus E.; Kubo, Michiaki; Mueller-Nurasyid, Martina; Lyytikäinen, Leo-Pekka; Smith, Jonathan D.; Van Wagoner, David R.; Seppälä, Ilkka; Bis, Joshua C.; Gustav Smith, J.; Perz, Siegfried; Psaty, Bruce M.; Malik, Rainer; Ridker, Paul M.; Magnani, Jared W.; Horimoto, Andrea R. V. R.; Klarin, Derek; Harris, Tamara B.; Perez, Marco; Launer, Lenore J.; Shoemaker, M. Benjamin; Sinisalo, Juha; Padmanabhan, Sandosh; Doerr, Marcus; Haessler, Jeffrey; Aeschbacher, Stefanie; Bartz, Traci M.; Waldenberger, Melanie; Thériault, Sébastien; Lichtner, Peter; Arendt, Marina; Krieger, Jose E.; Yao, Jie; Kähönen, Mika; Risch, Lorenz; Radmanesh, Farid; Mansur, Alfredo J.; Peters, Annette; Weiss, Stefan; Smith, Blair H.; van der Harst, Pim; Lind, Lars; Teumer, Alexander; Scott, Stuart A.; Lu, Yingchang; Choi, Seung Hoan; Bottinger, Erwin B.; Weng, Lu-Chen; Hernesniemi, Jussi; Lindgren, Cecilia M.; Clauss, Sebastian; Wong, Jorge A.; De, Arking; Deo, Rajat; Huang, Jie; Eskola, Markku; Rader, Daniel J.; Morris, Andrew P.; Ford, Ian; Shah, Svati H.; Reiner, Alex P.; Delgado, Graciela; Sun, Albert; Chen, Lin Y.; Chen, Yii-Der Ida; Sandhu, Roopinder K.; Boerwinkle, Eric; Av, Smith; Eisele, Lewin; Hagemeijer, Yanick P.; Lannfelt, Lars; Rost, Natalia; Verweij, Niek; Anderson, Christopher D.; Taylor, Kent D.; Siland, Joylene E.; Lin, Henry J.; Campbell, Archie; Magnusson, Patrik K.; Porteous, David; Hocking, Lynne J.; Vlachopoulou, Efthymia; Cm, Albert; Pedersen, Nancy L.; Nikus, Kjell; Orho-Melander, Marju; Hamsten, Anders; Heeringa, Jan; Denny, Joshua C.; Kriebel, Jennifer; Darbar, Dawood; Newton-Cheh, Christopher; Shaffer, Christian; Macfarlane, Peter W.; Li, Man; Heilmann-Heimbach, Stefanie; Almgren, Peter; Huang, Paul L.; Sotoodehnia, Nona; Soliman, Elsayed Z.; Uitterlinden, Andre G.; Hofman, Albert; Franco, Oscar H.; Völker, Uwe; Jöckel, Karl-Heinz; Sinner, Moritz F.; Nr, Tucker; Guo, Xiuqing; Dichgans, Martin; Ingelsson, Erik; Kooperberg, Charles; Melander, Olle; Loos, Ruth J. F.; Laurikka, Jari; Conen, David; Rosand, Jonathan; Lokki, Marja-Liisa; Kathiresan, Sekar; Pereira, Alexandre; Jukema, J. Wouter; Hayward, Caroline; Rotter, Jerome I.; März, Winfried; Lehtimäki, Terho; Stricker, Bruno H.; Chung, Mina K.; Felix, Stephan B.; Gudnason, Vilmundur; Alonso, Alvaro; Roden, Dan M.; Kääb, Stefan; Chasman, Daniel I.; Metastroke, Consortium Isgc; Heckbert, Susan R.; Benjamin, Emelia J.; Tanaka, Toshihiro; Charge, Neurology Working Grp; Lunetta, Kathryn L.; Lubitz, Steven A.; Consortium, AFGen; Ellinor, Patrick T.

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Ingrid Elisabeth Christophersen
Christophersen et al., 2017

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Nature Research, Nature Genetics, 6(49), p. 946-952

DOI: 10.1038/ng.3843

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@article{Christophersen2017,
  author = {Christophersen, Ingrid E. and Lin, Honghuang and Ie, Christophersen and Rienstra, Michiel and Li, Molong and Roselli, Carolina and Arking, Dan E. and Müller-Nurasyid, Martina and Smith, J. Gustav and Smith, Albert V. and Yin, Xiaoyan and Albert, Christine M. and Dörr, Marcus and Geelhoed, Bastiaan and Tucker, Nathan R. and Barnard, John and Bihlmeyer, Nathan A. and Low, Siew-Kee and Weeke, Peter E. and Brody, Jennifer A. and Niemeijer, Maartje N. and Trompet, Stella and Hopewell, Jemma C. and Debette, Stephanie and Chauhan, Ganesh and Huffman, Jennifer and Chaffin, Mark and Yang, Qiong and Worrall, Bradford B. and Gustafsson, Stefan and Paré, Guillaume and Kamatani, Yoichiro and Schurmann, Claudia and Kleber, Marcus E. and Kubo, Michiaki and Mueller-Nurasyid, Martina and Lyytikäinen, Leo-Pekka and Smith, Jonathan D. and Van Wagoner, David R. and Seppälä, Ilkka and Bis, Joshua C. and Gustav Smith, J. and Perz, Siegfried and Psaty, Bruce M. and Malik, Rainer and Ridker, Paul M. and Magnani, Jared W. and Horimoto, Andrea R. V. R. and Klarin, Derek and Harris, Tamara B. and Perez, Marco and Launer, Lenore J. and Shoemaker, M. Benjamin and Sinisalo, Juha and Padmanabhan, Sandosh and Doerr, Marcus and Haessler, Jeffrey and Aeschbacher, Stefanie and Bartz, Traci M. and Waldenberger, Melanie and Thériault, Sébastien and Lichtner, Peter and Arendt, Marina and Krieger, Jose E. and Yao, Jie and Kähönen, Mika and Risch, Lorenz and Radmanesh, Farid and Mansur, Alfredo J. and Peters, Annette and Weiss, Stefan and Smith, Blair H. and van der Harst, Pim and Lind, Lars and Teumer, Alexander and Scott, Stuart A. and Lu, Yingchang and Choi, Seung Hoan and Bottinger, Erwin B. and Weng, Lu-Chen and Hernesniemi, Jussi and Lindgren, Cecilia M. and Clauss, Sebastian and Wong, Jorge A. and De, Arking and Deo, Rajat and Huang, Jie and Eskola, Markku and Rader, Daniel J. and Morris, Andrew P. and Ford, Ian and Shah, Svati H. and Reiner, Alex P. and Delgado, Graciela and Sun, Albert and Chen, Lin Y. and Chen, Yii-Der Ida and Sandhu, Roopinder K. and Boerwinkle, Eric and Av, Smith and Eisele, Lewin and Hagemeijer, Yanick P. and Lannfelt, Lars and Rost, Natalia and Verweij, Niek and Anderson, Christopher D. and Taylor, Kent D. and Siland, Joylene E. and Lin, Henry J. and Campbell, Archie and Magnusson, Patrik K. and Porteous, David and Hocking, Lynne J. and Vlachopoulou, Efthymia and Cm, Albert and Pedersen, Nancy L. and Nikus, Kjell and Orho-Melander, Marju and Hamsten, Anders and Heeringa, Jan and Denny, Joshua C. and Kriebel, Jennifer and Darbar, Dawood and Newton-Cheh, Christopher and Shaffer, Christian and Macfarlane, Peter W. and Li, Man and Heilmann-Heimbach, Stefanie and Almgren, Peter and Huang, Paul L. and Sotoodehnia, Nona and Soliman, Elsayed Z. and Uitterlinden, Andre G. and Hofman, Albert and Franco, Oscar H. and Völker, Uwe and Jöckel, Karl-Heinz and Sinner, Moritz F. and Nr, Tucker and Guo, Xiuqing and Dichgans, Martin and Ingelsson, Erik and Kooperberg, Charles and Melander, Olle and Loos, Ruth J. F. and Laurikka, Jari and Conen, David and Rosand, Jonathan and Lokki, Marja-Liisa and Kathiresan, Sekar and Pereira, Alexandre and Jukema, J. Wouter and Hayward, Caroline and Rotter, Jerome I. and März, Winfried and Lehtimäki, Terho and Stricker, Bruno H. and Chung, Mina K. and Felix, Stephan B. and Gudnason, Vilmundur and Alonso, Alvaro and Roden, Dan M. and Kääb, Stefan and Chasman, Daniel I. and Metastroke, Consortium Isgc and Heckbert, Susan R. and Benjamin, Emelia J. and Tanaka, Toshihiro and Charge, Neurology Working Grp and Lunetta, Kathryn L. and Lubitz, Steven A. and Consortium, AFGen and Ellinor, Patrick T.},
  doi = {10.1038/ng.3843},
  journal = {Nature Genetics},
  month = {apr},
  pages = {946-952},
  title = {Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation},
  url = {https://oadoi.org/10.1038/ng.3843},
  volume = {49},
  year = {2017}
}

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