Published in
American Association for the Advancement of Science, Science Translational Medicine, 393(9), 2017
DOI: 10.1126/scitranslmed.aal1669
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Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase
Journal article published in 2017 by
Shira G. Ziegler 
,
Carlos R. Ferreira,
Elena Gallo MacFarlane ,
Ryan C. Riddle ,
Ryan E. Tomlinson,
Emily Y. Chew ,
Ludovic Martin,
Chen-Ting Ma,
Eduard Sergienko,
Anthony B. Pinkerton ,
José Luis Millán,
William A. Gahl ,
Harry C. Dietz
,
Carlos R. Ferreira,
Elena Gallo MacFarlane ,
Ryan C. Riddle ,
Ryan E. Tomlinson,
Emily Y. Chew ,
Ludovic Martin,
Chen-Ting Ma,
Eduard Sergienko,
Anthony B. Pinkerton ,
José Luis Millán,
William A. Gahl ,
Harry C. Dietz
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Abstract
Ectopic calcification in PXE integrates both local and systemic perturbations of extracellular ATP metabolism and can be attenuated with a TNAP inhibitor.