Published in
American Society of Hematology, Blood Advances, 16(2), p. 2145-2155, 2018
DOI: 10.1182/bloodadvances.2017008508
Links
Tools
RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists
Journal article published in 2018 by
Peisong Ma 
,
Shuchi Gupta ,
Sara Sampietro,
Daniel DeHelian ,
Valerie Tutwiler,
Alan Tang,
Timothy J. Stalker,
Lawrence F. Brass
,
Shuchi Gupta ,
Sara Sampietro,
Daniel DeHelian ,
Valerie Tutwiler,
Alan Tang,
Timothy J. Stalker,
Lawrence F. Brass
This paper is made freely available by the publisher.
Full text: Download
Preprint: archiving forbidden
Postprint:
archiving forbidden
Data provided by 
Abstract
Key Points Following vascular injury, RGS10 tunes the platelet signaling network to ensure the establishment of an effective hemostatic plug. It does this by limiting Gq- and Gi2-dependent signaling and by agonist-selective effects on responses to thrombin, ADP, and TxA2.