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American Society of Hematology, Blood, 15(131), p. 1720-1729

DOI: 10.1182/blood-2017-09-805499

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Extracellular vesicle–mediated transfer of constitutively active MyD88L265Pengages MyD88wtand activates signaling

Journal article published in 2018 by Mateja Manček-Keber, Duško Lainšček, Mojca Benčina, Jiaji G. Chen ORCID, Rok Romih, Zachary R. Hunter ORCID, Steven P. Treon ORCID, Roman Jerala ORCID
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

Key Points MyD88L265P is present in the EVs secreted by WM cancer cells and triggers signaling in the recipient cells. MyD88-containing EVs shape the proinflammatory microenvironment in the bone marrow.