Published in
American Society of Hematology, Blood, 6(132), p. 622-634, 2018
DOI: 10.1182/blood-2017-12-820779
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GPIbα is required for platelet-mediated hepatic thrombopoietin generation
Journal article published in 2018 by
Miao Xu 
,
June Li,
Miguel Antonio Dias Neves,
Guangheng Zhu,
Naadiya Carrim,
Ruoying Yu,
Sahil Gupta,
John Marshall,
Ori Rotstein,
Jun Peng,
Ming Hou,
Shinji Kunishima,
Jerry Ware,
Donald R. Branch,
Alan H. Lazarus
and other authors.
,
June Li,
Miguel Antonio Dias Neves,
Guangheng Zhu,
Naadiya Carrim,
Ruoying Yu,
Sahil Gupta,
John Marshall,
Ori Rotstein,
Jun Peng,
Ming Hou,
Shinji Kunishima,
Jerry Ware,
Donald R. Branch,
Alan H. Lazarus
and other authors.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
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Abstract
Key PointsPlatelet GPIbα induces hepatic TPO generation and maintains TPO levels in blood. Antiextracellular GPIbα antibodies decrease TPO generation and may affect TPO levels in immune-mediated thrombocytopenias.