Published in
American Society of Hematology, Blood, p. blood-2018-03-840132
DOI: 10.1182/blood-2018-03-840132
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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Journal article published in 2018 by
Brian A. Walker 
,
Konstantinos Mavrommatis,
Christopher P. Wardell ,
T. Cody Ashby,
Michael Bauer,
Faith E. Davies,
Adam Rosenthal,
Hongwei Wang,
Pingping Qu,
Antje Hoering,
Mehmet Samur,
Fadi Towfic,
Maria Ortiz,
Erin Flynt,
Zhinuan Yu
and other authors.
,
Konstantinos Mavrommatis,
Christopher P. Wardell ,
T. Cody Ashby,
Michael Bauer,
Faith E. Davies,
Adam Rosenthal,
Hongwei Wang,
Pingping Qu,
Antje Hoering,
Mehmet Samur,
Fadi Towfic,
Maria Ortiz,
Erin Flynt,
Zhinuan Yu
and other authors.
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Abstract
Key Points Using the largest set of patients with newly diagnosed myeloma, we identified 63 mutated driver genes. We identified oncogenic dependencies, particularly relating to primary translocations, indicating a nonrandom accumulation of genetic hits.