Published in
American Association for the Advancement of Science, Science Translational Medicine, 379(9), 2017
DOI: 10.1126/scitranslmed.aah3560
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Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
Journal article published in 2017 by
Whijae Roh 
,
Pei-Ling Chen ,
Alexandre Reuben ,
Christine N. Spencer ,
Peter A. Prieto,
John P. Miller ,
Vancheswaran Gopalakrishnan ,
Feng Wang,
Zachary A. Cooper ,
Sangeetha M. Reddy,
Curtis Gumbs ,
Latasha Little ,
Qing Chang,
Wei-Shen Chen ,
Khalida Wani
and other authors.
,
Pei-Ling Chen ,
Alexandre Reuben ,
Christine N. Spencer ,
Peter A. Prieto,
John P. Miller ,
Vancheswaran Gopalakrishnan ,
Feng Wang,
Zachary A. Cooper ,
Sangeetha M. Reddy,
Curtis Gumbs ,
Latasha Little ,
Qing Chang,
Wei-Shen Chen ,
Khalida Wani
and other authors.
This paper is available in a repository.
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Abstract
Profiling of melanoma patients treated with checkpoint blockade reveals TCR clonality and copy number loss as correlates of therapeutic response.