Elsevier, Bioorganic and Medicinal Chemistry Letters, 11(5), p. 1125-1130, 1995
DOI: 10.1016/0960-894x(95)00178-v
Full text: Unavailable
17-(3-pyridyl)androsta-5,16-dien-3β-ol, a nanomolar inhibitor of the P450 enzyme C17α-hydroxylase/C17-20 lyase, is a target for prostate cancer chemotherapy. A model is presented for the inhibitor docked into the structure of the enzyme. © 1995.