Dunes commonly dominate the bed of sandy rivers and they are of central importance in predicting flow resistance and water levels. In the present study, we show that by using light-weight polystyrene particles as substrate in a laboratory setting, promising morphodynamic similarity is obtained between dunes in shallow flow (flume) and deep flow (field) conditions. In particular, results from our flume experiments show that dune lee-side angles, which are crucial in turbulence production and energy dissipation, better approximate dune lee-side angles observed in natural channels. Furthermore, dune height evolution towards upper stage plane bed observed in the present experimental study, closely follows dune height evolution as observed in world’s large rivers.