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Hindawi, International Journal of Inflammation, (2013), p. 1-4

DOI: 10.1155/2013/601424

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Metabolic Acidosis Treatment as Part of a Strategy to Curb Inflammation

Journal article published in 2013 by Tales Rubens de Nadai ORCID, Mariane Nunes de Nadai, Agnes Afrodite Sumarelli Albuquerque ORCID, Marco Tulio Menezes de Carvalho, Andrea Carla Celotto, Paulo Roberto Barbosa Evora
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abnormalities in systemic acid-base balance may induce significant changes in the immune response, and they may play a significant role in the development or maintenance of immune dysfunction. Different forms of acidosis (metabolic and respiratory) and even different types of metabolic acidosis (hyperchloremic and lactic) may produce different effects on immune function. If alkalization has, or not, some effect on inflammation control is still a matter of speculation. Studies concerning these subjects are limited justifying this paper.