Dissemin is shutting down on January 1st, 2025

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American Society of Hematology, Blood, 25(130), p. 2718-2727

DOI: 10.1182/blood-2017-05-781849

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Immune reconstitution and survival of 100 SCID patients post–hematopoietic cell transplant: a PIDTC natural history study

Journal article published in 2017 by Jennifer Heimall, Logan Br, Jennifer M. Puck, Cowan Mj, Michael A. Pulsipher, Notarangelo Ld, Brent R. Logan, Morton J. Cowan, Griffith Lm, Puck Jm, Luigi D. Notarangelo, Kohn Db, Linda M. Griffith, Pulsipher Ma, Donald B. Kohn and other authors.
Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

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Abstract

Key Points Active infection pretransplant adversely impacts survival (81% in patients with active infection vs 95% in infection-free patients; P = .009). Preparative chemotherapy improved 1-year post-HCT median CD4 counts (P = .02) and freedom from IV immunoglobulin (P < .001).