Published in
American Society for Microbiology, Infection and Immunity, 10(86), 2018
DOI: 10.1128/iai.00213-18
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Desialylation of Platelets by Pneumococcal Neuraminidase A Induces ADP-Dependent Platelet Hyperreactivity
Journal article published in 2018 by
Vesla Kullaya 
,
Marien I. de Jonge,
Jeroen D. Langereis ,
Christa E. van der Gaast-De Jongh,
Christian Büll,
Gosse J. Adema,
Dirk Lefeber,
Amelieke J. Cremers ,
Blandina T. Mmbaga,
Phillip G. de Groot,
Quirijn de Mast ,
Andre J. van der Ven
,
Marien I. de Jonge,
Jeroen D. Langereis ,
Christa E. van der Gaast-De Jongh,
Christian Büll,
Gosse J. Adema,
Dirk Lefeber,
Amelieke J. Cremers ,
Blandina T. Mmbaga,
Phillip G. de Groot,
Quirijn de Mast ,
Andre J. van der Ven
This paper is made freely available by the publisher.
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Abstract
Platelets are increasingly recognized to play a role in the complications of Streptococcus pneumoniae infections. S. pneumoniae expresses neuraminidases, which may alter glycans on the platelet surface.