Published in
American Society of Hematology, Blood, 17(129), p. 2395-2407
DOI: 10.1182/blood-2016-08-736041
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Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia
Journal article published in 2017 by
Sarah K. Tasian 
,
Saad S. Kenderian,
Feng Shen,
Marco Ruella,
Olga Shestova,
Miroslaw Kozlowski,
Yong Li,
April Schrank-Hacker,
Jennifer J. D. Morrissette,
Martin Carroll,
Carl H. June,
Stephan A. Grupp,
Saar Gill
,
Saad S. Kenderian,
Feng Shen,
Marco Ruella,
Olga Shestova,
Miroslaw Kozlowski,
Yong Li,
April Schrank-Hacker,
Jennifer J. D. Morrissette,
Martin Carroll,
Carl H. June,
Stephan A. Grupp,
Saar Gill
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
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Abstract
Key Points Depletion of CD123-redirected CAR T cells with monoclonal antibodies preserves leukemia remission in human AML xenograft models. AML CAR T-cell depletion enhances feasibility of subsequent allogeneic stem cell transplantation.