Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

Mathew, Nimitha R.; Baumgartner, Francis; Braun, Lukas; O'Sullivan, David; Thomas, Simone; Waterhouse, Miguel; Müller, Tony A.; Hanke, Kathrin; Taromi, Sanaz; Apostolova, Petya; Illert, Anna L.; Melchinger, Wolfgang; Duquesne, Sandra; Schmitt-Graeff, Annette; Osswald, Lena; Yan, Kai-Li; Weber, Arnim; Tugues, Sonia; Spath, Sabine; Pfeifer, Dietmar; Follo, Marie; Claus, Rainer; Lübbert, Michael; Rummelt, Christoph; Bertz, Hartmut; Wäsch, Ralph; Haag, Johanna; Schmidts, Andrea; Schultheiss, Michael; Bettinger, Dominik; Thimme, Robert; Ullrich, Evelyn; Tanriver, Yakup; Vuong, Giang Lam; Arnold, Renate; Hemmati, Philipp; Wolf, Dominik; Ditschkowski, Markus; Jilg, Cordula; Wilhelm, Konrad; Leiber, Christian; Gerull, Sabine; Halter, Jörg; Lengerke, Claudia; Pabst, Thomas; Schroeder, Thomas; Kobbe, Guido; Rösler, Wolf; Doostkam, Soroush; Meckel, Stephan; Stabla, Kathleen; Metzelder, Stephan K.; Halbach, Sebastian; Brummer, Tilman; Hu, Zehan; Dengjel, Joern; Hackanson, Björn; Schmid, Christoph; Holtick, Udo; Scheid, Christof; Spyridonidis, Alexandros; Stölzel, Friedrich; Ordemann, Rainer; Müller, Lutz P.; Sicre-De-Fontbrune, Flore; Ihorst, Gabriele; Kuball, Jürgen; Ehlert, Jan E.; Feger, Daniel; Wagner, Eva-Maria; Cahn, Jean-Yves; Schnell, Jacqueline; Kuchenbauer, Florian; Bunjes, Donald; Chakraverty, Ronjon; Richardson, Simon; Gill, Saar; van der Velden, Walter; Kröger, Nicolaus; Ayuk, Francis; Vago, Luca; Ciceri, Fabio; Müller, Antonia M.; Kondo, Takeshi; Teshima, Takanori; Klaeger, Susan; Kuster, Bernhard; Kim, Dennis (Dong Hwan); Weisdorf, Daniel; Van Der Velden, W.; Dörfel, Daniela; Bethge, Wolfgang; Hilgendorf, Inken; Hochhaus, Andreas; Andrieux, Geoffroy; Börries, Melanie; Busch, Hauke; Magenau, John; Reddy, Pavan; Labopin, Myriam; Antin, Joseph H.; Henden, Andrea S.; Hill, Geoffrey R.; Kennedy, Glen A.; von Bubnoff, Nikolas; Bar, Merav; Sarma, Anita; McLornan, Donal; Mufti, Ghulam; Oran, Betul; Rezvani, Katayoun; Shah, Omid; Negrin, Robert S.; Nagler, Arnon; Prinz, Marco; Burchert, Andreas; Neubauer, Andreas; Beelen, Dietrich; Mackensen, Andreas; Von Bubnoff, N.; Herr, Wolfgang; Becher, Burkhard; Socié, Gerard; Caligiuri, Michael A.; Ruggiero, Eliana; Bonini, Chiara; Häcker, Georg; Duyster, Justus; Finke, Jürgen; Pearce, Erika; Blazar, Bruce R.; Zeiser, Robert

Dissemin
Rainer Claus
Mathew et al., 2018

Published in

Nature Research, Nature Medicine, 3(24), p. 282-291, 2018

DOI: 10.1038/nm.4484

Tools

Export citation

Format

@article{Mathew2018,
  author = {Mathew, Nimitha R. and Baumgartner, Francis and Braun, Lukas and O'Sullivan, David and Thomas, Simone and Waterhouse, Miguel and Müller, Tony A. and Hanke, Kathrin and Taromi, Sanaz and Apostolova, Petya and Illert, Anna L. and Melchinger, Wolfgang and Duquesne, Sandra and Schmitt-Graeff, Annette and Osswald, Lena and Yan, Kai-Li and Weber, Arnim and Tugues, Sonia and Spath, Sabine and Pfeifer, Dietmar and Follo, Marie and Claus, Rainer and Lübbert, Michael and Rummelt, Christoph and Bertz, Hartmut and Wäsch, Ralph and Haag, Johanna and Schmidts, Andrea and Schultheiss, Michael and Bettinger, Dominik and Thimme, Robert and Ullrich, Evelyn and Tanriver, Yakup and Vuong, Giang Lam and Arnold, Renate and Hemmati, Philipp and Wolf, Dominik and Ditschkowski, Markus and Jilg, Cordula and Wilhelm, Konrad and Leiber, Christian and Gerull, Sabine and Halter, Jörg and Lengerke, Claudia and Pabst, Thomas and Schroeder, Thomas and Kobbe, Guido and Rösler, Wolf and Doostkam, Soroush and Meckel, Stephan and Stabla, Kathleen and Metzelder, Stephan K. and Halbach, Sebastian and Brummer, Tilman and Hu, Zehan and Dengjel, Joern and Hackanson, Björn and Schmid, Christoph and Holtick, Udo and Scheid, Christof and Spyridonidis, Alexandros and Stölzel, Friedrich and Ordemann, Rainer and Müller, Lutz P. and Sicre-De-Fontbrune, Flore and Ihorst, Gabriele and Kuball, Jürgen and Ehlert, Jan E. and Feger, Daniel and Wagner, Eva-Maria and Cahn, Jean-Yves and Schnell, Jacqueline and Kuchenbauer, Florian and Bunjes, Donald and Chakraverty, Ronjon and Richardson, Simon and Gill, Saar and van der Velden, Walter and Kröger, Nicolaus and Ayuk, Francis and Vago, Luca and Ciceri, Fabio and Müller, Antonia M. and Kondo, Takeshi and Teshima, Takanori and Klaeger, Susan and Kuster, Bernhard and Kim, Dennis (Dong Hwan) and Weisdorf, Daniel and Van Der Velden, W. and Dörfel, Daniela and Bethge, Wolfgang and Hilgendorf, Inken and Hochhaus, Andreas and Andrieux, Geoffroy and Börries, Melanie and Busch, Hauke and Magenau, John and Reddy, Pavan and Labopin, Myriam and Antin, Joseph H. and Henden, Andrea S. and Hill, Geoffrey R. and Kennedy, Glen A. and von Bubnoff, Nikolas and Bar, Merav and Sarma, Anita and McLornan, Donal and Mufti, Ghulam and Oran, Betul and Rezvani, Katayoun and Shah, Omid and Negrin, Robert S. and Nagler, Arnon and Prinz, Marco and Burchert, Andreas and Neubauer, Andreas and Beelen, Dietrich and Mackensen, Andreas and Von Bubnoff, N. and Herr, Wolfgang and Becher, Burkhard and Socié, Gerard and Caligiuri, Michael A. and Ruggiero, Eliana and Bonini, Chiara and Häcker, Georg and Duyster, Justus and Finke, Jürgen and Pearce, Erika and Blazar, Bruce R. and Zeiser, Robert},
  doi = {10.1038/nm.4484},
  journal = {Nature Medicine},
  month = {feb},
  pages = {282-291},
  title = {Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells},
  url = {http://www.nature.com/articles/nm.4484.pdf},
  volume = {24},
  year = {2018}
}

Download

Export citation

Search in Google Scholar