The present study was aimed to evaluate the use of increasing levels of castor bean cake detoxified with calcium hydroxide in diets for pigs at growing and finishing phases on performance, diet digestibility, weight of digestive organs, carcass traits, and economic evaluation. A total of 40 barrows with 44.59 ± 5.16 kg initial weight were fed diets with 0%, 7%, 14%, and 21% detoxified castor bean cake. Increasing levels of detoxified castor bean cake in diets resulted in linear worsening in the average daily gain of the pigs. Dry matter, crude protein, and gross energy digestibilities were adversely affected by the levels of detoxified castor bean cake. A linear decrease in loin eye area and ham yield was detected depending on detoxified castor bean cake inclusion levels. Although the detoxified castor bean cake had no effect on the assessed economic variables, its use in diets for growing and finishing pigs is not recommended.